Not really, not anything real noticeable, for the simple fact a 427 ran a fairly violent intake duration.
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And speaking of retarded cam timing, Ford & Chevy both retarded the timing a couple of degrees
on some V-8's back in mid 70's through 80's. Cloyes offered 2 types of timing sets, The oem 2*
degrees retarded and OEM straight up. Most people including mechanics at the time didn't realize
there was two correct sets--including the parts guys.
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Retarded cam timing=a little better performance milage @ 2,500 to 3,000 rpm, highway speed.
Asvanced cam timing=a little better torque @ off idle to 2,500 or so.