On the upside - if you don't have a drain plug in the bottom of a housing, it can't fall out from vibration or from forgetting to tighten it!
Back in the bad ol' days when many vehicles had rear axle drain plugs in the bottom of the axle housing, it wasn't unusual for them to fall out on rough roads (corrugations/washboard), resulting in a full lubricant drain, followed shortly by a whining differential as it protested about the lack of lubricant!
My truckie neighbour ran a Cummins-powered KW running East-West, and is known to be a bit of a "rip, tear and bust" individual, with an accent on speed, rather than on accuracy and thoroughness!
He told me how one time, he did a rapid engine oil/filter change on the KW - his employee driver rolled up to do a trip to the East, and off he went.
Shortly afterwards, the truckie started having those horrible thoughts about whether he'd properly tightened the engine oil pan plug.
He managed to send through a message to one of the roadhouses along the way to get the employee driver to call him.
The driver got the message and called him, and he said to him, "Get underneath the engine, and make double sure I tightened that drain plug properly!"
The employee came back to him and said, "Yep, I checked it and it's tight! - all good!"
The next day, the driver called in and said, "You know that engine oil drain plug? I checked the one on the bottom of the oil pan, and didn't check the one on the side of the oil pan! It fell out and the engine is toast!!"